Protein measurements in venous plasma, earlobe capillary plasma and in plasma stored on filter paper

Author(s)
Benjamin Siart, Felipe Marques Souza de Oliveira, Qiujin Shen, Johan Björkesten, Thomas Pekar, Ralf Steinborn, Alfred Nimmerichter, Masood Kamali-Moghaddam, Bernard Wallner
Abstract

In this study, levels of inflammatory protein biomarkers in venous plasma, plasma derived from capillary blood from the earlobe, and capillary plasma stored as dried plasma spots (DPS) were compared. Samples from 12 male individuals were assessed with a panel of 92 inflammation-related proteins using multiplex proximity extension assay. Correlations between sample types varied greatly between analytes. A high correlation of ρ > 0.8 was observed between capillary plasma and DPS for 32 analytes. At this level of correlation, 13 analytes correlated between venous and capillary plasma and 5 analytes in the comparison of venous blood with DPS.

Organisation(s)
Department of Evolutionary Anthropology
External organisation(s)
Uppsala University, Fachhochschule Wiener Neustadt, Veterinärmedizinische Universität Wien
Journal
Analytical Biochemistry
Volume
566
Pages
146-150
No. of pages
5
ISSN
0003-2697
DOI
https://doi.org/10.1016/j.ab.2018.11.016
Publication date
02-2019
Peer reviewed
Yes
Austrian Fields of Science 2012
106051 Behavioural biology
Keywords
ASJC Scopus subject areas
Biophysics, Biochemistry, Molecular Biology, Cell Biology
Portal url
https://ucris.univie.ac.at/portal/en/publications/protein-measurements-in-venous-plasma-earlobe-capillary-plasma-and-in-plasma-stored-on-filter-paper(2c58fd0e-d179-407a-bbab-cb578b69649d).html