Population-specific, recent positive directional selection suggests adaptation of human male reproductive genes to different environmental conditions

Author(s)
Helmut Schaschl, Bernard Wallner
Abstract

Recent human transcriptomic analyses revealed a very large number of testis-enriched genes, many of which are involved in spermatogenesis. This comprehensive transcriptomic data lead us to the question whether positive selection was a decisive force influencing the evolution and variability of testis-enriched genes in humans. We used two methodological approaches to detect different levels of positive selection, namely episodic positive diversifying selection (i.e., past selection) in the human lineage within primate phylogeny, potentially driven by sperm competition, and recent positive directional selection in contemporary human populations, which would indicate adaptation to different environments.

Organisation(s)
Department of Evolutionary Anthropology, Department of Behavioral and Cognitive Biology
Journal
BMC Evolutionary Biology
Volume
20
ISSN
1471-2148
DOI
https://doi.org/10.1186/s12862-019-1575-0
Publication date
02-2020
Peer reviewed
Yes
Austrian Fields of Science 2012
106051 Behavioural biology
Portal url
https://ucris.univie.ac.at/portal/en/publications/populationspecific-recent-positive-directional-selection-suggests-adaptation-of-human-male-reproductive-genes-to-different-environmental-conditions(31a04f81-5738-4161-9e05-03f1f7abbd62).html